Vol. 5 No. 1 (2025): Issue 5
Articles

Impact of Krill Oil Supplementation on Alternate-Day Fasting in Adults With Overweight and Obesity: Findings From a Randomized Trial

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  • Mansour Alblaji,
  • Stuart R. Gray,
  • Taibah Almesbehi
Mansour Alblaji
Human Nutrition, School of Medicine, Dentistry and Nursing, College of Medical, Veterinary, and Life Sciences, University of Glasgow, Glasgow, UK
Stuart R. Gray
Department of Basic Health Sciences, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi Arabia
Taibah Almesbehi
Bio
DOI: https://doi.org/10.71070/jcbm.v5i1.143

Published 2025-08-17

Keywords

  • body composition,
  • caloric restriction,
  • long-chain n-3 polyunsaturated fatty acids,
  • muscle function,
  • weight loss

How to Cite

Alblaji, M., R. Gray, S., & Almesbehi, T. (2025). Impact of Krill Oil Supplementation on Alternate-Day Fasting in Adults With Overweight and Obesity: Findings From a Randomized Trial. Journal of Computational Biology and Medicine, 5(1). https://doi.org/10.71070/jcbm.v5i1.143

Abstract

Diet is widely recognized as an important determinant of health, yet the associations between individual macronutrients and mental health remain unclear. To address this, we conducted a cross-sectional study of 129 healthy adults using an online food frequency questionnaire along with validated measures of depression, anxiety, and early life experiences. Among participants, 31% reported moderate or severe anxiety and/or depression. Sugar-sweetened beverage intake was positively associated with depressive symptoms (β = 4.827; 95% CI: 0.954–8.7; p = 0.015), while dietary fibre intake was negatively associated with anxiety (β = –2.306; 95% CI: –3.791 to –0.82; p = 0.003). Moderate caffeine consumption (100–300 mg) was linked to reduced depression (β = –4.099; 95% CI: –7.049 to –1.15; p = 0.007), suggesting a possible U-shaped effect, and women reported higher rates of both depression and anxiety. We also observed preliminary evidence of an association between high-fructose corn syrup and depressive symptoms and a protective role of fibre against anxiety. Overall, these findings highlight specific dietary factors linked to mental health, warranting further prospective studies with repeated dietary assessments to confirm and extend these results.

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